Cell & Gene Therapy Center

Cell & Gene Therapy Center

The Cell & Gene Therapy Center at ATLATL is built to help teams design, develop, and advance cell and gene therapies from concept to preclinical readiness faster.
 
The platform integrates cell engineering, gene editing, viral vector development, process optimization, and analytical capabilities into a single, on-site execution environment. Scientists work side-by-side with technical experts, enabling real-time iteration, rapid troubleshooting, and efficient generation of proof-of-concept data.

Core Capabilities:

Cell Engineering & Gene Editing
CRISPR-based editing, viral transduction, and custom cell model development for therapeutic design and validation.
Cell Therapy Process Development
Optimization of cell expansion, activation, and differentiation for T cells, stem cells, and other therapeutic cell types.
Gene Delivery & Vector Development
Development and evaluation of viral (lentivirus, AAV) and non-viral delivery systems.
Functional & Potency Assays
Flow cytometry, cytotoxicity assays, and cytokine profiling to evaluate therapeutic activity.
Quality Control & Characterization
Identity, purity, viability, and safety testing to ensure robust and reproducible workflows.

Equipments:

Bio-Rad Gel Doc™ EZ System

Bio-Rad Gene Pulser Xcell

Bio-Rad QX200 AutoDG Droplet Digital PCR System

Bio-Rad T100 Thermal Cycler

Celetrix LE Cell Electroporation System

Leica Mateo TL digital transmitted light inverted microscope

Revvity Cellometer K2 Fluorescent Cell Counter

Miltenyi Biotec gentle MACS™ Octo Dissociator with Heater

Thermo Countess 3 Automated Cell Counter

Thermo NanoDrop™ OneC Spectrophotometer

Thermo SimpliAmp™ Thermal Cycler

R&D Applications:

CAR-T / TCR-T Development

Design, engineering, and validation of immune cell therapies

Gene Editing & Functional Genomics

Knockout/knock-in models and pathway validation

Stem Cell & iPSC Programs
Differentiation, disease modeling, and regenerative applications

Viral Vector Development

Lentivirus and AAV production, purification, and titration

Preclinical Evaluation

In vitro and ex vivo models, including co-culture and organoid systems

Process Scale-Up & Tech Transfer

Transition from research to pilot-scale production
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