Drug Screening Center

Drug Screening Center

The Drug Screening Center at ATLATL is built to help teams identify hits, validate targets, and generate proof-of-concept data faster.

The platform integrates automation, advanced detection technologies, and biologically relevant models into a single, on-site execution environment. Scientists can rapidly design and run experiments with minimal setup, enabling high-throughput, reproducible workflows and fast iteration.

By combining cell-based assays, organoid models, high-content imaging, and molecular analysis, the platform supports end-to-end workflows—from assay development and screening to hit validation and mechanism-of-action studies. Located within ATLATL’s bio-hubs, teams work side-by-side with technical experts, accelerating decision-making and reducing development risk.

Core Capabilities：

High-Throughput Screening (HTS)

Automated compound screening for rapid hit identification with high reproducibility.

Cell-Based & Organoid Assays

Functional and phenotypic assays using 2D cell systems and advanced 3D models.

Target Validation & MoA

Molecular and cellular analysis to confirm targets and understand mechanisms.

Biomolecular Interaction Analysis

SPR-based, label-free analysis of binding affinity, specificity, and kinetics.

Data Analysis & Hit Advancement

Integrated data processing and support for lead selection and early optimization.

Equipments:

ZUOFEI Automatic Liquid Handing Solution

Revvity Janus G3 Workstation

Revvity Zephyr Workstation

MD SpectraMax ABS Plus Microplate Reader

MD SpectraMax i3x Multi-Mode Microplate Reader

Revvity EnVision™ Microplate Reader

Revvity Operetta CLS High Content Imaing System

Tecan Spark Cyto Plate Reader

Thermo 7500 Real-Time PCR System

Roche LightCycler® 480 Real-Time PCR System

md spectramax abs plus microplate reader

md spectramax i3x multi mode microplate reader

revvity envision™ microplate reader

revvity janus g3 workstation

revvity operetta cls high content imaing system

revvity zephyr workstation

roche lightcycler® 480 real time pcr system

tecan spark cyto plate reader

thermo 7500 real time pcr system

zuofei automatic liquid handing solution

R&D Applications:

Small Molecule Discovery

High-throughput screening and dose–response profiling

Biologics & Antibody Development

Binding, potency, and functional validation

Oncology Drug Screening

Tumor models, co-culture systems, and organoids

Immunology & Inflammation

Immune cell assays and cytokine profiling

Gene & RNA Therapeutics Screening

CRISPR, siRNA, mRNA, and viral vector evaluation

Toxicology & Safety Assessment

Early detection of cytotoxicity and off-target effects