Introduction：
The Single-Cell & Spatial Biology Center at ATLATL is designed to help teams understand complex biology and identify the right targets faster.
By integrating spatial multi-omics with live single-cell functional analysis, the platform enables researchers to move from discovery to validation in a single workflow. Scientists can first map cell types, states, and microenvironment interactions directly in human tissues, and then isolate and test individual cells in real time to confirm function and therapeutic relevance.
Located within ATLATL’s bio-hubs, teams work side-by-side with technical experts, enabling rapid iteration and generation of decision-ready data. This closed-loop approach significantly reduces the gap between biological insight and therapeutic development, accelerating programs in oncology, immunology, and precision medicine.
Core Capabilities：
Spatial Multi-Omics Profiling
High-plex RNA and protein analysis in intact tissues, preserving spatial context and revealing cellular heterogeneity.
Single-Cell Functional Screening
Real-time isolation, culture, and monitoring of individual cells to evaluate secretion, cytotoxicity, and dynamic behavior.
Tumor Microenvironment Analysis
Mapping tumor–immune–stromal interactions to support target discovery and biomarker development.
Immune Profiling & Antibody Discovery
High-throughput screening of B and T cells for functional activity and therapeutic candidate selection.
Cell Therapy Development Support
Functional validation and selection workflows for CAR-T / TCR-T and other cell therapies.
Closed-Loop Discovery-to-Validation Workflow
Seamless integration of spatial discovery and functional testing to accelerate translational outcomes.
Equipment:
BRUKER CosMx Spatial Molecule Imager
BRUKER Beacon Optofluidic System
R&D Applications：
Target Discovery & Validation
Identify and validate biologically relevant targets
Oncology & Precision Medicine
Tumor microenvironment analysis and patient stratification
Immunology & Cell Therapy
Immune cell profiling and CAR-T / TCR-T workflows
Biomarker Discovery
Integrate spatial and functional data
Drug Screening Support
Evaluate response at single-cell resolution
English 
日本語 
简体中文 
Français 
Deutsch