{"id":3141,"date":"2026-04-13T21:37:30","date_gmt":"2026-04-13T13:37:30","guid":{"rendered":"https:\/\/www.atlatl.center\/?page_id=3141"},"modified":"2026-04-22T17:18:07","modified_gmt":"2026-04-22T09:18:07","slug":"cell-manufacturing-center","status":"publish","type":"page","link":"https:\/\/www.atlatl.center\/fr\/platforms\/cell-manufacturing-center\/","title":{"rendered":"Centre de Fabrication de Cellules"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"3141\" class=\"elementor elementor-3141\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-25d8c63 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"25d8c63\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-718d28b\" data-id=\"718d28b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5c7c2a2 elementor-widget elementor-widget-text-editor\" data-id=\"5c7c2a2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Les th\u00e9rapies cellulaires progressent rapidement, stimulant la demande d'une fabrication \u00e9volutive et standardis\u00e9e. La plateforme ATLATL exploite la technologie de syst\u00e8me ferm\u00e9 CliniMACS\u00ae pour traiter les th\u00e9rapies autologues et allog\u00e9niques avec une plus grande coh\u00e9rence et efficacit\u00e9. Prenant en charge la mise \u00e0 l'\u00e9chelle (scale-out) et l'augmentation de capacit\u00e9 (scale-up), et s'adaptant aux mod\u00e8les centralis\u00e9s ou de point de soins, la plateforme acc\u00e9l\u00e8re le passage du d\u00e9veloppement \u00e0 la commercialisation.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7ea64da elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"7ea64da\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5814e6a\" data-id=\"5814e6a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-34d2f5c elementor-widget elementor-widget-text-editor\" data-id=\"34d2f5c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Applications CliniMACS\u00ae Plus<\/strong><\/p><ul><li>Isolement des lymphocytes T : s\u00e9lection positive de CD4\/CD8<\/li><li>Cellule T : d\u00e9pl\u00e9tion des TCR \u03b1\/\u03b2<\/li><li>Cellules NK : d\u00e9pl\u00e9tion CD3 \/ enrichissement CD56<\/li><li>Isolement des Treg : enrichissement en CD25<\/li><li>Cellules B : d\u00e9pl\u00e9tion ou enrichissement de CD19<\/li><li>Isolation de HSC : enrichissement CD34<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-a18aeaf\" data-id=\"a18aeaf\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b2c34d1 elementor-widget elementor-widget-image\" data-id=\"b2c34d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"770\" height=\"353\" src=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/Picture2.png\" class=\"attachment-2048x2048 size-2048x2048 wp-image-3201\" alt=\"image2\" srcset=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/Picture2.png 770w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/Picture2-768x352.png 768w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/Picture2-18x8.png 18w\" sizes=\"(max-width: 770px) 100vw, 770px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c3e4456 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"c3e4456\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bc1e35f\" data-id=\"bc1e35f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-db88c14 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"db88c14\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f815b3b elementor-widget elementor-widget-heading\" data-id=\"f815b3b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><span><b>La plateforme CliniMACS Prodigy\u00ae<\/b><\/span><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-490b683 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"490b683\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-fabdfa3\" data-id=\"fabdfa3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eb6a699 elementor-widget elementor-widget-text-editor\" data-id=\"eb6a699\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"84\" data-end=\"262\">La plateforme CliniMACS Prodigy\u00ae int\u00e8gre toutes les \u00e9tapes cl\u00e9s de la fabrication des cellules T dans un syst\u00e8me ferm\u00e9 et automatis\u00e9, avec des flux de travail adapt\u00e9s \u00e0 diff\u00e9rents besoins th\u00e9rapeutiques :<\/p><ul data-start=\"264\" data-end=\"741\"><li data-section-id=\"8hofns\" data-start=\"264\" data-end=\"409\">Transduction des lymphocytes T (TCT) : L'approche standard pour la fabrication des CAR-T, permettant une transduction virale efficace et une administration de g\u00e8nes robuste.<\/li><li data-section-id=\"q2tgv\" data-start=\"410\" data-end=\"586\">Transduction de cellules T avec formulation automatis\u00e9e (TCTf) : \u00c9tend le flux de travail TCT avec des capacit\u00e9s int\u00e9gr\u00e9es de formulation et de remplissage pour une pr\u00e9paration pr\u00e9cise du produit final.<\/li><li data-section-id=\"casz78\" data-start=\"587\" data-end=\"741\">Transduction des lymphocytes T \u2013 Grande \u00c9chelle (TCT-GS) : Adapte le flux de travail TCT \u00e0 des volumes de culture plus importants, supportant la fabrication \u00e0 haute dose et \u00e0 grande \u00e9chelle.<\/li><\/ul><p data-start=\"743\" data-end=\"1026\">Con\u00e7us pour une production conforme aux BPF, ces flux de travail permettent la fabrication automatis\u00e9e et standardis\u00e9e de cellules T g\u00e9n\u00e9tiquement modifi\u00e9es. En minimisant la manipulation manuelle et les \u00e9tapes ouvertes, la plateforme garantit une production de cellules coh\u00e9rente et reproductible, adapt\u00e9e aux applications cliniques.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-bd43834\" data-id=\"bd43834\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6ac7157 elementor-widget elementor-widget-image\" data-id=\"6ac7157\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"534\" height=\"236\" src=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/MACS-e1776097896137.png\" class=\"attachment-large size-large wp-image-3202\" alt=\"Macs\" srcset=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/MACS-e1776097896137.png 534w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/MACS-e1776097896137-18x8.png 18w\" sizes=\"(max-width: 534px) 100vw, 534px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Cell-based therapies are rapidly advancing, driving demand for scalable, standardized manufacturing. ATLATL\u2019s platform leverages CliniMACS\u00ae closed-system technology to process both autologous and allogeneic therapies with greater consistency and efficiency. Supporting both scale-out and scale-up, and adaptable to centralized or point-of-care [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":752,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"left-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"normal-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-3141","page","type-page","status-publish"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/pages\/3141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/comments?post=3141"}],"version-history":[{"count":7,"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/pages\/3141\/revisions"}],"predecessor-version":[{"id":3970,"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/pages\/3141\/revisions\/3970"}],"up":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/pages\/752"}],"wp:attachment":[{"href":"https:\/\/www.atlatl.center\/fr\/wp-json\/wp\/v2\/media?parent=3141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}