{"id":3149,"date":"2026-04-13T21:39:31","date_gmt":"2026-04-13T13:39:31","guid":{"rendered":"https:\/\/www.atlatl.center\/?page_id=3149"},"modified":"2026-04-22T17:21:38","modified_gmt":"2026-04-22T09:21:38","slug":"drug-screening-center","status":"publish","type":"page","link":"https:\/\/www.atlatl.center\/de\/platforms\/drug-screening-center\/","title":{"rendered":"Drogenscreening-Zentrum"},"content":{"rendered":"
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Drogenscreening-Zentrum<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Das Drogen-Screening-Zentrum bei ATLATL ist darauf ausgelegt, Teams dabei zu unterst\u00fctzen, Hits zu identifizieren, Ziele zu validieren und Proof-of-Concept-Daten schneller zu generieren.<\/div>
Die Plattform integriert Automatisierung, fortschrittliche Detektionstechnologien und biologisch relevante Modelle in einer einzigen, lokalen Ausf\u00fchrungsumgebung. Wissenschaftler k\u00f6nnen Experimente mit minimalem Aufwand schnell entwerfen und durchf\u00fchren, was Hochdurchsatz- und reproduzierbare Arbeitsabl\u00e4ufe sowie eine schnelle Iteration erm\u00f6glicht.<\/div>
Durch die Kombination von zellbasierten Assays, Organoidmodellen, High-Content-Bildgebung und Molekularanalysen unterst\u00fctzt die Plattform End-to-End-Workflows \u2013 von der Assay-Entwicklung und dem Screening bis zur Trefferbest\u00e4tigung und Machbarkeitsstudien. In den Bio-Hubs von ATLATL arbeiten Teams Seite an Seite mit Fachexperten, um Entscheidungen zu beschleunigen und das Entwicklungsrisiko zu reduzieren.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kernkompetenzen:<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Hochdurchsatz-Screening (HTS)<\/b><\/div>
Automatisierte Wirkstoff-Screenings zur schnellen Trefferidentifikation mit hoher Reproduzierbarkeit.<\/div>
Zellbasierte & Organoid-Assays<\/b><\/div>
Funktionelle und ph\u00e4notypische Assays unter Verwendung von 2D Zellsysteme und fortschrittliche 3D-Modelle<\/b>.<\/div>
Zielvalidierung & Wirkmechanismus<\/b><\/div>
Molekulare und zellul\u00e4re Analysen zur Best\u00e4tigung von Zielmolek\u00fclen und zum Verst\u00e4ndnis von Mechanismen.<\/div>
Biomolekulare Interaktionsanalyse<\/b><\/div>
SPR-basierte, markierungsfreie Analyse von Bindungsaffinit\u00e4t, Spezifit\u00e4t und Kinetik.<\/div>
Datenanalyse und Hiterkennung<\/b><\/div>
Integrierte Datenverarbeitung und Unterst\u00fctzung f\u00fcr Lead-Auswahl und fr\u00fche Optimierung<\/b>.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ausr\u00fcstungen:\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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ZUOFEI Automatische Fl\u00fcssighandhabungsl\u00f6sung<\/p>

Revvity Janus G3 Workstation<\/p>

Revvity Zephyr Workstation<\/p>

MD SpectraMax ABS Plus Mikrotiterplattenleseger\u00e4t<\/p>

MD SpectraMax i3x Multi-Mode Mikrotiterplattenleser<\/p>

Revvity EnVision\u2122 Mikrotiterplatten-Leseger\u00e4t<\/p>

Revvity Operetta CLS High Content Imaging System<\/p>

Tecan Spark Cyto Plattenleseger\u00e4t<\/p>

Thermo 7500 Real-Time PCR System<\/p>

Roche LightCycler\u00ae 480 Echtzeit-PCR-System<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"MD<\/figure><\/div>
\"MD<\/figure><\/div>
\"revvity<\/figure><\/div>
\"Revvity<\/figure><\/div>
\"Revvity<\/figure><\/div>
\"revvity<\/figure><\/div>
\"Roche<\/figure><\/div>
\"Tecan<\/figure><\/div>
\"Thermo<\/figure><\/div>
\"Zuofei<\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t
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F&E-Anwendungen<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Entdeckung kleiner Molek\u00fcle<\/b><\/p>

Hochdurchsatz-Screening und Dosis-Wirkungs-Profilierung<\/p>

Biologika & Antik\u00f6rperentwicklung<\/b><\/p>

Bindung, Wirksamkeit und funktionelle Validierung<\/p>

Onkologische Wirkstoffpr\u00fcfung<\/b><\/p>

Tumormodelle, Kokultursysteme und Organoide<\/p>

Immunologie & Entz\u00fcndung<\/b><\/p>

Immunzellassays und Zytokinprofilierung<\/p>

Gen- und RNA-Therapeutika-Screening<\/b><\/p>

CRISPR, siRNA, mRNA und virale Vektor-Evaluierung<\/p>

Toxikologie & Sicherheitsbewertung<\/b><\/p>

Fr\u00fcherkennung von Zytotoxizit\u00e4t und Off-Target-Effekten<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Drug Screening Center The Drug Screening Center at ATLATL is built to help teams identify hits, validate targets, and generate proof-of-concept data faster.The platform integrates automation, advanced detection technologies, and biologically relevant models into a single, on-site execution environment. Scientists […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":752,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"left-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"normal-width-container","site-content-style":"default","site-sidebar-style":"boxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"659","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-3149","page","type-page","status-publish"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/comments?post=3149"}],"version-history":[{"count":10,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3149\/revisions"}],"predecessor-version":[{"id":3976,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3149\/revisions\/3976"}],"up":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/752"}],"wp:attachment":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/media?parent=3149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}