{"id":3143,"date":"2026-04-13T21:37:58","date_gmt":"2026-04-13T13:37:58","guid":{"rendered":"https:\/\/www.atlatl.center\/?page_id=3143"},"modified":"2026-04-22T17:20:09","modified_gmt":"2026-04-22T09:20:09","slug":"cell-gene-therapy-center","status":"publish","type":"page","link":"https:\/\/www.atlatl.center\/de\/platforms\/cell-gene-therapy-center\/","title":{"rendered":"Zell- und Gentherapiezentrum"},"content":{"rendered":"
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Zell- und Gentherapiezentrum<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Das ATLATL Cell & Gene Therapy Center wurde entwickelt, um Teams dabei zu unterst\u00fctzen, Zell- und Gentherapien schneller vom Konzept bis zur pr\u00e4klinischen Reife zu entwickeln, zu erforschen und voranzutreiben.<\/div>
\u00a0<\/div>
Die Plattform integriert Zelltechnik, Gen-Editierung, Entwicklung viraler Vektoren, Prozessoptimierung und analytische F\u00e4higkeiten in einer einzigen, standortinternen Ausf\u00fchrungsumgebung. Wissenschaftler arbeiten Seite an Seite mit technischen Experten, was Echtzeit-Iterationen, schnelle Fehlerbehebung und die effiziente Generierung von Proof-of-Concept-Daten erm\u00f6glicht.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Kernkompetenzen:<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Zell-Engineering & Gen-Editierung<\/b><\/div>
CRISPR-basierte Genomeditierung, virale Transduktion und Entwicklung kundenspezifischer Zellmodelle f\u00fcr das therapeutische Design und die Validierung.<\/div>
Zelltherapieprozessentwicklung<\/b><\/div>
Optimierung der Zellvergr\u00f6\u00dferung, -aktivierung und -differenzierung f\u00fcr T-Zellen, Stammzellen und andere therapeutische Zelltypen.<\/div>
Gentherapie & Vektor-Entwicklung<\/b><\/div>
Entwicklung und Evaluierung von viralen (Lentivirus, AAV) und nicht-viralen Transportsystemen.<\/div>
Funktionelle & Potenz-Assays<\/b><\/div>
Durchflusszytometrie, Zytotoxizit\u00e4tstests und Zytokinprofilierung zur Bewertung der therapeutischen Aktivit\u00e4t.<\/div>
Qualit\u00e4tskontrolle und Charakterisierung<\/b><\/div>
Identit\u00e4ts-, Reinheits-, Lebensf\u00e4higkeits- und Sicherheitstests zur Gew\u00e4hrleistung robuster und reproduzierbarer Arbeitsabl\u00e4ufe.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ausr\u00fcstungen:<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Bio-Rad Gel Doc\u2122 EZ System<\/p>

Bio-Rad Gene Pulser Xcell<\/p>

Bio-Rad QX200 AutoDG Droplet Digital PCR System<\/p>

Bio-Rad T100 Thermocycler<\/p>

Celetrix LE Zell-Elektroporationssystem<\/p>

Leica Mateo TL digital transmitted light inverted microscope<\/p>

Revvity Cellometer K2 Fluoreszenz-Zellz\u00e4hler<\/p>

Miltenyi Biotec gentle MACS\u2122 Octo Dissociator mit Heizung<\/p>

Thermo Z\u00e4hlautomat 3<\/p>

Thermo NanoDrop\u2122 OneC Spektrophotometer<\/p>

Thermo SimpliAmp\u2122 Thermocycler<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"thermo<\/figure><\/div>
\"Thermo<\/figure><\/div>
\"thermo<\/figure><\/div>
\"revvity<\/figure><\/div>
\"miltenyi<\/figure><\/div>
\"Leica<\/figure><\/div>
\"celetrix<\/figure><\/div>
\"Bio-Rad<\/figure><\/div>
\"Bio-Rad<\/figure><\/div>
\"Bio-Rad<\/figure><\/div>
\"Bio-Rad<\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t
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<\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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F&E-Anwendungen<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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CAR-T \/ TCR-T Entwicklung<\/b><\/p>

Design, Entwicklung und Validierung von Immunzelltherapien<\/span><\/p>

Gen-Editierung & Funktionelle Genomik<\/b><\/p>

Knockout-\/Knock-in-Modelle und Validierung von Signalwegen<\/span><\/p>

Stammzell- & iPSZ-Programme<\/b><\/div>
Differenzierung, Krankheitsmodellierung und regenerative Anwendungen<\/span><\/div><\/div>

Virale Vektor-Entwicklung<\/b><\/p>

Lenti- und AAV-Produktion, -Aufreinigung und -Titration<\/div><\/div>

Pr\u00e4klinische Bewertung<\/b><\/p>

In-vitro- und Ex-vivo-Modelle, einschlie\u00dflich Kokultur- und Organoidsystemen<\/div><\/div>

Prozessskalierung und Technologietransfer<\/b><\/p>

Umstellung von der Forschung zur Pilotproduktion<\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Cell & Gene Therapy Center The Cell & Gene Therapy Center at ATLATL is built to help teams design, develop, and advance cell and gene therapies from concept to preclinical readiness faster.\u00a0The platform integrates cell engineering, gene editing, viral vector […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":752,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"left-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"normal-width-container","site-content-style":"default","site-sidebar-style":"boxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"659","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-3143","page","type-page","status-publish"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3143","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/comments?post=3143"}],"version-history":[{"count":10,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3143\/revisions"}],"predecessor-version":[{"id":3973,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3143\/revisions\/3973"}],"up":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/752"}],"wp:attachment":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/media?parent=3143"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}