{"id":3139,"date":"2026-04-13T21:37:03","date_gmt":"2026-04-13T13:37:03","guid":{"rendered":"https:\/\/www.atlatl.center\/?page_id=3139"},"modified":"2026-04-22T17:23:40","modified_gmt":"2026-04-22T09:23:40","slug":"exosome-ev-center","status":"publish","type":"page","link":"https:\/\/www.atlatl.center\/de\/platforms\/exosome-ev-center\/","title":{"rendered":"Exosom & EV-Zentrum"},"content":{"rendered":"
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Exosom- & EV-Zentrum<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Das Exosome & EV Center bei ATLATL hilft Teams dabei, exosomalbasierte Therapeutika und Verabreichungssysteme schneller zu entwickeln und zu validieren.<\/p>

Exosomen bieten einen vielversprechenden Ansatz f\u00fcr zellfreie Therapien und gezielte Verabreichung mit Vorteilen in Biokompatibilit\u00e4t, Stabilit\u00e4t und Gewebepenetration (einschlie\u00dflich der Blut-Hirn-Schranke). Bei ATLATL bieten wir eine integrierte End-to-End-Plattform, die Isolierung, Charakterisierung, funktionelle Validierung und skalierbare Produktion umfasst.<\/p>

In unseren Bio-Hubs arbeiten Wissenschaftler Seite an Seite mit technischen Experten, was eine schnelle Iteration und die Generierung entscheidungsreifer Daten erm\u00f6glicht \u2013 von der fr\u00fchen Forschung bis zur translationalen Entwicklung.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Kernkompetenzen:<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Isolierung & Reinigung<\/strong><\/p>

Hocheffiziente, automatisierte Isolierung aus vielf\u00e4ltigen Probentypen (Zellkultur, Plasma, Urin und mehr), die hohe Reinheit, Ausbeute und erhaltene Bioaktivit\u00e4t gew\u00e4hrleistet.<\/p>

Charakterisierung & Qualit\u00e4tskontrolle<\/strong><\/p>

Umfassende Analyse einschlie\u00dflich:<\/p>

\u2022Gr\u00f6\u00dfe und Konzentration (NTA)<\/p>

\u2022Morphologie (TEM \/ Kryo-EM)<\/p>

\u2022Oberfl\u00e4chenmarker (FACS, WB, NanoFCM)<\/p>

\u2022Stabilit\u00e4t und Ladung (Zeta-Potential)<\/p>

Funktionale Validierung<\/strong><\/p>

Beurteilung der biologischen Aktivit\u00e4t mittels zellbasierte und In-vivo-Modelle<\/strong>, unterst\u00fctzt durch Multi-Omics- und mechanistische Studien.<\/p>

Ingenieurwesen & Therapeutische Entwicklung<\/strong><\/p>

Unterst\u00fctzung f\u00fcr Wirkstoffbeladung, zielgerichtete Modifikation und Markierung<\/strong>, wodurch die Entwicklung von exosomalen Abgabesystemen erm\u00f6glicht wird.<\/p>

Skalierung & Produktionsunterst\u00fctzung<\/strong><\/p>

Von der Kleinforschung bis Pilot und Gro\u00dfserienproduktion<\/strong>, mit Arbeitsabl\u00e4ufen, die auf Konsistenz und Reproduzierbarkeit ausgelegt sind.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Ausr\u00fcstungen:\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Bio-Rad ChemiDoc MP Bildgebungssystem<\/p>

FEI Tecnai G2 T12 Transmissionselektronenmikroskop<\/p>

HUIXIN AUTOMATIC EXOSOME ISOLATION SYSTEM EXODUS H-2800<\/p>

HUIXIN AUTOMATISCHES EXOSOM-ISOLIERUNGSSYSTEM EXODUS H-600<\/p>

HUIXIN AUTOMATISCHES EXOSOM-ISOLIERUNGSSYSTEM EXODUS H300<\/p>

Miltenyi Biotec MACSQuant\u00ae Analyzer 16<\/p>

NanoFCM Nano Durchflusszytometrie<\/p>

Nikon Konfokales Laserscanning-Mikroskop AX<\/p>

PARTICLE METRIX ZETAVIEW Partikelanalysator<\/p>

Resuntech NanoCoulter Partikelanalysator<\/p>

Thermo iBind\u2122 Flex Western<\/p>

Thermo iBlot 3 Transfersystem<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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\"Bio-Rad<\/figure><\/div>
\"FEI<\/figure><\/div>
\"huixin<\/figure><\/div>
\"huixin<\/figure><\/div>
\"huixin<\/figure><\/div>
\"miltenyi<\/figure><\/div>
\"Nano<\/figure><\/div>
\"Nikon<\/figure><\/div>
\"Particle<\/figure><\/div>
\"Resuntech<\/figure><\/div>
\"thermo<\/figure><\/div>
\"Thermo<\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t
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F&E-Anwendungen<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Wirkstofffreisetzungssysteme<\/strong><\/p>

Exosomenbasierte Verabreichung f\u00fcr RNA, Proteine und kleine Molek\u00fcle<\/p>

Zellfreie Therapien<\/strong><\/p>

Stammzell-abgeleitete Exosomen f\u00fcr regenerative und immunmodulatorische Anwendungen<\/p>

Biomarker-Entdeckung<\/strong><\/p>

Fl\u00fcssigbiopsie und Krankheits\u00fcberwachung<\/p>

Zielvalidierung & Mechanismusstudien<\/strong><\/p>

Funktionelle und Multi-Omics-Analyse<\/p>

Translationale Entwicklung<\/strong><\/p>

Br\u00fcckenbildung von der Forschung zur pr\u00e4klinischen und fr\u00fchen klinischen Validierung<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Exosome & EV Center The Exosome & EV\u00a0Center at ATLATL is designed to help teams develop and validate exosome-based therapeutics and delivery systems faster. Exosomes offer a promising approach for cell-free therapies and targeted delivery, with advantages in biocompatibility, stability, and […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":752,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"left-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"normal-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-3139","page","type-page","status-publish"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3139","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/comments?post=3139"}],"version-history":[{"count":10,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3139\/revisions"}],"predecessor-version":[{"id":3980,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/3139\/revisions\/3980"}],"up":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/pages\/752"}],"wp:attachment":[{"href":"https:\/\/www.atlatl.center\/de\/wp-json\/wp\/v2\/media?parent=3139"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}