{"id":3104,"date":"2026-04-17T17:04:49","date_gmt":"2026-04-17T09:04:49","guid":{"rendered":"https:\/\/www.atlatl.center\/?page_id=3104"},"modified":"2026-04-17T17:57:05","modified_gmt":"2026-04-17T09:57:05","slug":"single-cell-spatial-biology-center","status":"publish","type":"page","link":"https:\/\/www.atlatl.center\/cn\/platforms\/single-cell-spatial-biology-center\/","title":{"rendered":"Single Cell Research Center"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"3104\" class=\"elementor elementor-3104\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2ba2494 e-flex e-con-boxed e-con e-parent\" data-id=\"2ba2494\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0a0a6a6 elementor-widget elementor-widget-heading\" data-id=\"0a0a6a6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Introduction\uff1a<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ff9f6e9 e-flex e-con-boxed e-con e-parent\" data-id=\"ff9f6e9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2805d54 elementor-widget elementor-widget-text-editor\" data-id=\"2805d54\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The Single-Cell &amp; Spatial Biology Center at ATLATL is designed to help teams understand complex biology and identify the right targets faster.&nbsp;<\/p>\n<p>By integrating spatial multi-omics with live single-cell functional analysis, the platform enables researchers to move from discovery to validation in a single workflow. Scientists can first map cell types, states, and microenvironment interactions directly in human tissues, and then isolate and test individual cells in real time to confirm function and therapeutic relevance.<\/p><p>&nbsp;Located within ATLATL\u2019s bio-hubs, teams work side-by-side with technical experts, enabling rapid iteration and generation of decision-ready data. This closed-loop approach significantly reduces the gap between biological insight and therapeutic development, accelerating programs in oncology, immunology, and precision medicine.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-eb6b590 e-flex e-con-boxed e-con e-parent\" data-id=\"eb6b590\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-733f22e elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"733f22e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-062806c e-flex e-con-boxed e-con e-parent\" data-id=\"062806c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e2a9bad elementor-widget elementor-widget-heading\" data-id=\"e2a9bad\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Core Capabilities\uff1a\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e563ac5 e-flex e-con-boxed e-con e-parent\" data-id=\"e563ac5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-18ff31a elementor-widget elementor-widget-text-editor\" data-id=\"18ff31a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Spatial<\/b><strong> Multi-Omics Profiling<\/strong><\/p><p>High-plex RNA and protein analysis in intact tissues, preserving spatial context and revealing cellular heterogeneity.\u00a0<\/p><p><strong>Single-Cell Functional Screening<\/strong><\/p><p>Real-time isolation, culture, and monitoring of individual cells to evaluate secretion, cytotoxicity, and dynamic behavior.\u00a0<\/p><p><strong>Tumor Microenvironment Analysis<\/strong><\/p><p>Mapping tumor\u2013immune\u2013stromal interactions to support target discovery and biomarker development.<\/p><p><strong>Immune Profiling &amp; Antibody Discovery<\/strong><\/p><p>High-throughput screening of B and T cells for functional activity and therapeutic candidate selection.\u00a0<\/p><p><b>Cell Therapy Development Support<\/b><\/p><p>Functional validation and selection workflows for CAR-T \/ TCR-T and other cell therapies.\u00a0<\/p><p><b>Closed-Loop Discovery-to-Validation Workflow\u00a0<\/b><\/p><p>Seamless integration of spatial discovery and functional testing to accelerate translational outcomes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d32a88b elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"d32a88b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ec09015 e-flex e-con-boxed e-con e-parent\" data-id=\"ec09015\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a5f497b elementor-widget elementor-widget-heading\" data-id=\"a5f497b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Equipment:\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8571204 e-flex e-con-boxed e-con e-parent\" data-id=\"8571204\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c449f78 elementor-widget elementor-widget-text-editor\" data-id=\"c449f78\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>BRUKER CosMx Spatial Molecule Imager <br \/>BRUKER Beacon Optofluidic System<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-fa70422 e-grid e-con-boxed e-con e-parent\" data-id=\"fa70422\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5239a0a elementor-widget elementor-widget-image\" data-id=\"5239a0a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"768\" height=\"638\" src=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-CosMx-Spatial-Molecule-Imager-768x638.png\" class=\"attachment-medium_large size-medium_large wp-image-3441\" alt=\"bruker cosmx spatial molecule imager\" srcset=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-CosMx-Spatial-Molecule-Imager-768x638.png 768w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-CosMx-Spatial-Molecule-Imager-14x12.png 14w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-CosMx-Spatial-Molecule-Imager.png 1024w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7444e18 elementor-widget elementor-widget-image\" data-id=\"7444e18\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1022\" height=\"971\" src=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-Beacon-Optofluidic-System.png\" class=\"attachment-large size-large wp-image-3517\" alt=\"bruker beacon optofluidic system\" srcset=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-Beacon-Optofluidic-System.png 1022w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-Beacon-Optofluidic-System-768x730.png 768w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/BRUKER-Beacon-Optofluidic-System-13x12.png 13w\" sizes=\"(max-width: 1022px) 100vw, 1022px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-cb548bc e-flex e-con-boxed e-con e-parent\" data-id=\"cb548bc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5ba8f49 elementor-widget elementor-widget-image\" data-id=\"5ba8f49\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1024\" height=\"577\" src=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/1-1024x577.jpg\" class=\"attachment-large size-large wp-image-3536\" alt=\"1\" srcset=\"https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/1-1024x577.jpg 1024w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/1-768x433.jpg 768w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/1-18x10.jpg 18w, https:\/\/www.atlatl.center\/wp-content\/uploads\/2026\/04\/1.jpg 1031w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-455e71b e-flex e-con-boxed e-con e-parent\" data-id=\"455e71b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bf103d1 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"bf103d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8b51750 e-flex e-con-boxed e-con e-parent\" data-id=\"8b51750\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-afddb2d elementor-widget elementor-widget-heading\" data-id=\"afddb2d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">R&amp;D Applications\uff1a\n<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4fe8726 e-flex e-con-boxed e-con e-parent\" data-id=\"4fe8726\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-783c1b2 elementor-widget elementor-widget-text-editor\" data-id=\"783c1b2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Target Discovery &amp; Validation<\/strong><\/p><p>Identify and validate biologically relevant targets<\/p><p><strong>Oncology &amp; Precision Medicine<\/strong><\/p><p>Tumor microenvironment analysis and patient stratification<\/p><p><strong>Immunology &amp; Cell Therapy<\/strong><\/p><p>Immune cell profiling and CAR-T \/ TCR-T workflows<\/p><p><strong>Biomarker Discovery<\/strong><\/p><p>Integrate spatial and functional data<\/p><p><strong>Drug Screening Support<\/strong><\/p><p>Evaluate response at single-cell resolution<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Introduction\uff1a The Single-Cell &amp; Spatial Biology Center at ATLATL is designed to help teams understand complex biology and identify the right targets faster.&nbsp; By integrating spatial multi-omics with live single-cell functional analysis, the platform enables researchers to move from discovery [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":752,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","site-sidebar-layout":"left-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"normal-width-container","site-content-style":"default","site-sidebar-style":"boxed","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"659","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-3104","page","type-page","status-publish"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/pages\/3104","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/comments?post=3104"}],"version-history":[{"count":9,"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/pages\/3104\/revisions"}],"predecessor-version":[{"id":3545,"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/pages\/3104\/revisions\/3545"}],"up":[{"embeddable":true,"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/pages\/752"}],"wp:attachment":[{"href":"https:\/\/www.atlatl.center\/cn\/wp-json\/wp\/v2\/media?parent=3104"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}